![]() Interesting interview with Peter Kelsey, Emmy and Grammy winning Audio Engineer on Disney’s Dog with a Blog (and much much more). Interesting interview with Jason Fitzpatrick, DP, Co-Producer and Director of Mile Mile and a Half discussing the movie and what else is coming from The Muir Project.ġ1. LiquidHike Interview show with Jools Farrell Quartermaster, Lead and Medic for and from Sea Shepherd Sydney Australia discussing Sea Shepherds and Minke Whales and her involvement with them.ġ0. Interesting Interview with Ani Alexander from Armenia, Host of the Write 2B Read Podcast and owner of PublishMyBook.Today, discussing Writing and Reading Books.ĩ. ![]() Interesting Interview with Jeff King from Muse School CA in Calabasas California about their Solar educational program.Ĩ. Tool Talk with Michael Paine from discussing Periscope the live streaming video tool for Twitter broadcasting.ħ. Interesting Interview with Mike Johnson from Robotz Overlord Podcast discussing Robots and are they taking away our jobs!Ħ. Windows alternative to Fission is WavPad.ĥ. Windows alternative to Audio Hijack is Total Recorder. Tool Talk with Judy Reagan from Listeners Digest Podcast, discussing Mac and Windows Audio Editing Tools (Audio Hijack/Fission/Audacity). Interesting Interview with Shaun Waksman from Tel Aviv, Israel discussing Israeli startups, his company Coupon Roller and more.ĬouponRoller is the fun way to save when shopping online! Win great savings and amazing prizes!Ĥ. Questions about Podcasts? Read my article about How to Listen to a Podcast here: Intro and Tool Talk with Dave Bullis from Dave Bullis Podcast discuss Evaer, a tool for recording Skype (while we used it to record Skype!)Ģ. Intro part 2 and Tool Talk with Dawn Casey-Rowe, Author and Educator, blogger at, discuss Scrivener, a software used for writing fiction on Mac and Windows.ģ. This chemistry has proven itself to be superior in satisfying many criteria (e.g., biocompatibility, selectivity, yield, stereospecificity, and so forth) thus, one can expect it will consequently become a more routine strategy in the near future for a wide range of applications.PLEASE CLICK HERE to subscribe to the Michele the Trainer Show podcast on iTunes ![]() This review concludes that click chemistry is not the perfect conjugation and assembly technology for all applications, but provides a powerful, attractive alternative to conventional chemistry. Bifunctional chelating agents for several radionuclides useful for positron emission tomography and single-photon emission computed tomography imaging have also been prepared by using click chemistry. In radiochemistry, selective radiolabeling of biomolecules in cells and living organisms for imaging and therapy has been realized by this technology. Bioconjugation via click chemistry is rigorously employed in proteomics and nucleic research. Click chemistry has found increasing applications in all aspects of drug discovery in medicinal chemistry, such as for generating lead compounds through combinatorial methods. These reactions can be used to modify one cellular component while leaving others unharmed or untouched. The copper-catalyzed Huisgen cycloaddition, azide-alkyne dipolar cycloaddition, Staudinger ligation, and azide-phosphine ligation each possess these unique qualities. Second, the reactions proceed with ease under mild nontoxic conditions, such as at room temperature and, usually, in water. First, click reactions are bio-orthogonal neither the reactants nor their product's functional groups interact with functionalized biomolecules. Two important characteristics make click chemistry so attractive for assembling compounds, reagents, and biomolecules for preclinical and clinical applications. This update also discusses click chemistry reactions that proceed rapidly with high selectivity, specificity, and yield. This update summarizes the growing application of “click” chemistry in diverse areas such as bioconjugation, drug discovery, materials science, and radiochemistry.
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